ace_inhibitor

Phase 2 data. Binary variable indicating whether a drug from the ace inhibitor class was prescribed. 0: No 1: Yes

Categorical

aneamia

Phase 2 data. Binary variable indicating whether a drug from the anemia medication class was prescribed. 0 = No; 1 = Yes;

Categorical

antidepressants

Phase 2 data. Binary variable indicating whether a drug from the antidepressant class was prescribed. 0 = No; 1 = Yes;

Categorical

asthma_BA

Phase 2 data. Binary variable indicating whether a drug from the asthma: beta agonist class was prescribed. 0 = No; 1 = Yes;

Categorical

asthma_other

Phase 2 data. Binary variable indicating whether a drug from the asthma: other class was prescribed. 0 = No; 1 = Yes;

Categorical

asthma_steroids

Phase 2 data. Binary variable indicating whether a drug from the asthma: steroid class was prescribed. 0 = No; 1 = Yes;

Categorical

beta_blocker

Phase 2 data. Binary variable indicating whether a drug from the beta blocker class was prescribed. 0 = No; 1 = Yes;

Categorical

calcium_channel_blocker

Phase 2 data. Binary variable indicating whether a drug from the calcium channel blocker class was prescribed. 0 = No; 1 = Yes;

Categorical

diuretic

Phase 2 data. Binary variable indicating whether a drug from the diuretic class was prescribed. 0: No 1: Yes

Categorical

A1. On medication

A1. Are you taking any tablets or medicines at the moment? derived from GQ_V3.0_24/04: 2=Yes; 3=No;-1=left blank

Categorical

A2. ACE inhibitor

A2. Current self-reported meds - ACE inhibitor (eg perindopril enalapril lisinipril ramipril) derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Any self-reported medications

A2. Current self-reported meds - Any self-reported meds including unclassified meds: 1) weight loss drugs (orlistat/xenital) 2) drugs for smoking cessation / alcoholism / nasal discomfort / non-specific migraine 3) device for contraception 4) tamoxifen zoledex anastrozole exemestane or other anti-cancer drugs 5) related to specific organs (eg thyroid prostate bladder lung eye bone skin joint) unless noted on pain killers or autoimmune diseases. derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Angiotensin receptor blocker

A2. Current self-reported meds - Angio II receptor blocker (eg losartan olmesartan telmisartan valsartan) derived from GQ_V3.0_24/04: 2=yes self-reported;1=left blank

Categorical

A2. Aspirin

A2. Current self-reported meds - Aspirin derived from GQ_V3.0_24/04: 2=yes self-reported;-3=yes for pain/non-cardiac purpose;-1=left blank

Categorical

A2. Drugs for autoimmune diseases

A2. Current self-reported meds - Drugs for an autoimmune disease (eg carbimazole azathioprine dovobet fludrocortisone hydroxychloroquine methotrexate sulfasalazine) including: 1) gastro-intestinal conditions with a reason for Colitis or Coeliac disease 2) rheumatoid arthritis / psoriasis / systemic lupus erythematosus 3) multiple sclerosis 4) Addisons or Graves or Hashimotos diseases -- not including non-specific arthritis osteoarthritis asthma gout irritable-bowel syndrome and other immunological diseases without autoimmunity derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Beta blocker

A2. Current self-reported meds - Beta blocker (eg atenolol bisoprolol carvediol levobunolol emtoprolol sotalol propranolol) not including beta-blokers used as an eye drop derived from GQ_V3.0_24/04: 2=yes self-reported;5=yes for psychiatric symptoms rather than migraine;-3=yes for migraine;-1=left blank

Categorical

A2. Drugs for irritable bowel syndrome or constipation or others

A2. Current self-reported meds - Drugs related to bowel conditions (alverine azathioprine buscopan lactulose lansoprazole mebeverine senna) including laxatives or IBS or others: marked if use of drugs for gastro-intestinal conditions indicated IBS Colitis Coeliac disease or Crohns disease derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Any cardiovascular drugs except blood-clotting drug such as tranexamte

A2. Current self-reported meds - Any cardiovascular drugs except blood-clotting drug (eg tranexamic acid) for menstrual blood loss. Broad categories are lipid-lowering drugs / ace inhibitors / ARB / beta blockers / diuretics / nitrates / Ca channele blockers / anticoagulants derived from GQ_V3.0_24/04: 2=yes self-reported;-5=yes indicated for non-cardiac use (eg beta-blockers for migraine);-1=left blank

Categorical

A2. Drugs acting on the central nervous system

A2. Current self-reported meds - Any drugs acting on a central nervous system including 1) pain killers 2) psychiatric disorders 3) acid reflax derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Anti-depressant for depression mood anxiety or stress

A2. Current self-reported meds - Anti-depressant coded for depression anxiety stress panic attack (eg citalopram dosulepin duloxetine escitalopram fluoxetine mirtazapine paroxetine prozac seroxat quetiapine sertraline venlafaxine zopiclone) derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Diuretics

A2. Current self-reported meds - Diuretics (eg frusemide hydrochlorothiazide indapamide spironolactone zestoretic) including diuretic drugs used for water retention - not including ones used as eye drop derived from GQ_V3.0_24/04: 2=yes self-reported -1=left blank

Categorical

A2. Anti-diabetic medications (metformin) for polycystic ovary syndrome

A2. Current self-reported meds - Anti-diabetic meds (metformin) - all for polycystic ovary syndrome - participants should be free from diabetes at baseline. derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Drugs for gastric conditions

A2. Current self-reported meds - Drugs for gastric conditions (eg gaviscon lansoprazole omeprazole ranitidine) including acid reflux a heartburn symptom or others caused by a gastrointestinal side-effect of other drugs derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Herbal supplements including non-herbal ones (eg ginko)

A2. Current self-reported meds - Herbal supplements including plant oils for menopausal symptoms or other specific conditions (eg black cohosh primrose oil St Johns wort) - also including non-herbal plant-origin supplements (ginko garlic and others). derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Exogenous hormone including testosterone - not for endometriosis

A2. Current self-reported meds - Exogenous hormone use (GQV1_A3HRT accounted for) (eg estradiol elleste climesse climagest sandrena premarine premique progynova tibolone vagefem provera testosterone) 1) including testosteron use among men 2) not including non-hormonal agents for menopausal conditions (drugs for osteoporosis / psychiatric drugs / St Johns Wort / primrose oil / black cohosh) 3) not including exogenous hormone use for endometriosis or for excess menstual blood loss 4) including HRT requiring transdermal dosage derived from GQ_V3.0_24/04: 2=yes self-reported;3=no self-reported;-1=left blank

Categorical

A2. Drugs against infection

A2. Current self-reported meds - Drugs (eg flucoxacillin lymecycline aciclovir metronidazole amoxicillin ) against 1) fungal infection including terbinafine 2) topical abnormality with use of lymecycline / minocycline / ocytetracycline 3) urinary tract infection 4) HIV derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Drugs for inflammation including NSAIDS antihistamine and others

A2. Current self-reported meds - Drugs for inflammatory conditions (not including eczema) 1) irritable bowel syndrome crohn coeliac disease and colitus 2) asthma 3) inflammatory arthritis including gout non-autoimmune diseases and autoimmune diseases 4) topical medicine if specifically lupus or psoriasis was noted 5) hay fever / allergy / epipen for anaphylaxis 7) use of NSAIDS 8) antihistamine drugs (eg promethazine hydroxyzine acrivastine desloratadine fexofenadine levocetirizine loratadine mizolastine) derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Any lipid lowering drug (including omega-3 PUFA as BNF defines)

A2. Current self-reported meds - Any lipid lowering drug (including omega-3 PUFA as BNF lists). Bile acid sequestrants are not included if use for a intestinal disorder was specified derived from GQ_V3.0_24/04: 2=yes self-reported;1=left blank

Categorical

A2. Nitrates including meds for transdermal dosage

A2. Current self-reported meds - Nitrates (eg trinitrate GTNspray nicorandil) including meds for transdermal dosage - considered as a cardiac drug unless notified derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. NSAIDs for any purpose not including aspirin (gq_med_asp)/topical NSAIDs

A2. Current self-reported meds - NSAIDs for any purpose (eg celecoxib diclofenac etodolac ibuprofen meloxicam naprosyn omeprazole) 1) not including aspirin (see gq_med_asp) 2) not including topical ones (eg eumovate cream) 3) coded in use of a gastrointestinal med against NSAID use derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Dieatry supplements (oils vitamins minerals) for any reasons

A2. Current self-reported meds - Dieatry supplements (oils vitamins minerals) (eg iron calcium zinc vitamin D) derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Oral contraceptive not including non-oral ones

A2. Current self-reported meds - Oral contraceptives (eg cerazetta cilest depo gedarel loestrin marvelon micronor ovranette yasmin) 1) not including non-oral contraception eg (implanon mirena coil) 2) including cerazette for any reasons 3) birth control interpreted as oral contraceptive use 4) not including contraceptive drugs used for endometriosis or abnormal menstruation derived from GQ_V3.0_24/04: 2=yes self-reported;-7=not applicable/answered but undetermined;-1=left blank

Categorical

A2. NSAIDs or others used for pain as gq_med_pain

A2. Current self-reported meds - NSAIDs or others used for pain as gq_med_pain - including aspirin and beta-blocker used against migrane or for migraine profilaxis derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Any pain killers not classified as NSAIDs/aspirin/b-blockers

A2. Current self-reported meds - Any pain killers not classified as NSAIDs or aspirin (eg paracetamol almotriptan eletriptan frovatriptan naratriptan rizatriptan sumatriptan zolmitriptan pizotifen) or beta-blockers (propranol used for migraine) derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Drugs to aid sleeping - not necessarily sleeping disorder

A2. Current self-reported meds - Drugs to aid sleeping (etmazapam mirtazapine zopiclone) - mixed with a drug acting on central nervous system to suppress pain or other discomfort derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

A2. Statin

A2. Current self-reported meds - Statin (eg atorvastatin pravastatin rosuvastatin and simvastatin) derived from GQ_V3.0_24/04: 2=yes self-reported;-1=left blank

Categorical

lipid_lowering

Phase 2 data. Binary variable indicating whether a drug from the lipid lowering agent class was prescribed. 0: No 1: Yes

Categorical

metformin

Phase 2 data. Binary variable indicating whether a drug from the metforminr class was prescribed. 0: No 1: Yes

Categorical